CD19 anticorps

N° du produit ABIN370860

Cet anticorps anti-CD19 Monoclonal Souris (Clone MB19-1) (ABIN370860) détecte spécifiquement CD19 dans FACS et IP. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour CD19 anticorps (ABIN370860)

Antigène: CD19 (CD19 Molecule (CD19))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD19 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: MB19-1

Détail du produit anti-CD19 anticorps

Specificité: This antibody is specific to CD19 B cell differentiation antigen (Mr. 95 kDa)

Attributs du produit: Synonyms: Leu-12, B-cell marker, Differentiation antigen CD19, B-lymphocyte surface antigen B4

Purification: Purified

Immunogène: CD19+ mouse pre-B cell line, 300. 19. (Ref. 1)

Isotype: IgA

Information d'application

Indications d'application: Flow Cytometry. (Ref.1-3)Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD19

Antigène: CD19 (CD19 Molecule (CD19))

Autre désignation: CD19

Sujet: CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e., B220+/CD43+/HSA+) through fully differentiated B cell stages. (Ref.1-7) Terminally differentiated plasma cells do not express CD19.1 In humans, the CD19 Molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. (Ref.3,4) All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. (Ref.1,7) Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. (Ref.7)Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12

ID gène: 12478

UniProt: P25918

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway