CD86 anticorps (FITC)

N° du produit ABIN371013

Cet anticorps anti-CD86 est un anticorps Rat Monoclonal détectant CD86 dans FACS. Adapté pour Souris.

Aperçu rapide pour CD86 anticorps (FITC) (ABIN371013)

Antigène: CD86

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD86 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: GL1

Détail du produit anti-CD86 anticorps (FITC)

Specificité: This antibody recognises CD86, the B7-2 co-stimulatory molecule and a ligand for CD28 and CD152/CTLA-4.

Attributs du produit: Synonyms: CD28LG2, B70, FUN-1, BU63, T-lymphocyte activation antigen CD86, Activation B7-2antigen, CTLA-4 counter-receptor B7.2

Immunogène: LPS-activated mouse B cells. (Ref. 1)

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1-7)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD86

Antigène: CD86

Autre désignation: CD86

Sujet: CD86 (also known as B7-2) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. (Ref.1-5) CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. (Ref.1,5) CD86, along with CD80/B7-1, is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152/CTLA-4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. (Ref.1-9). The monoclonal antibody GL1 blocks mixed lymphocyte reactions and stimulation of T cells by antigen-presenting cells. (Ref.1,3,5)Synonyms: Activation B7-2 antigen, B7.2, B70, BU63, CD28LG2, CTLA-4 counter-receptor B7.2, FUN-1, T-lymphocyte activation antigen CD86

ID gène: 12524

UniProt: P42082

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation