LAMP1 anticorps

N° du produit ABIN371199

Cet anticorps anti-LAMP1 est un anticorps Rat Monoclonal détectant LAMP1 dans WB, FACS, IP, IHC (fro) et IEM. Adapté pour Souris.

Aperçu rapide pour LAMP1 anticorps (ABIN371199)

Antigène: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp LAMP1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoelectron Microscopy (IEM)

Clone: 1D4B

Détail du produit anti-LAMP1 anticorps

Specificité: This antibody is specific to CD107a/LAMP-1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa).

Réactivité croisée (Details): Species reactivity (tested):Mouse

Attributs du produit: Synonyms: LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1, CD107Antigen-like Family Member A

Purification: Purified

Immunogène: Plasma membrane fraction of mouse embryo NIH3T3 cell line. (Ref. 1)

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: < / = 1 μg/10^6 cells. (Ref.5)Immunohistochemistry on Frozen Sections. (Ref.5)Immunoaffinity Chromatography. (Ref.2)Western blot. (Ref.5)Immunoprecipitation. (Ref.1,3)Immunoelectron Microscopy. (Ref.6)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur LAMP1

Antigène: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Autre désignation: CD107a / LAMP1

Sujet: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. (Ref.1) It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. (Ref.2) CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. (Ref.3) LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. (Ref.4)Synonyms: CD107 Antigen-like Family Member A, LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1

ID gène: 16783

UniProt: P11438

Pathways: Autophagy