CD3 anticorps
Aperçu rapide pour CD3 anticorps (ABIN371285)
Antigène
Voir toutes CD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognizes Porcine CD3e (Mr. 20 kDa). The Monoclonal antibody PPT3 is Mitogenic when presented to peripheral blood mononuclear cells in immobilized form. (Ref.1)
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Attributs du produit
- Synonyms: T3/Leu-4, T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4
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Purification
- Purified
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Isotype
- IgG1
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Indications d'application
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Flow Cytometry. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections). Immunoprecipitation In vitro activation of T cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- CD3
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Autre désignation
- CD3
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Sujet
- CD3 epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains (designated as gamma, delta, epsilon, zeta and eta) ranging in size from 16-28 kDa. CD3 epsilon is closely associated with the T cell antigen receptor (TCR), and is present on thymocytes, CD8+ and CD4+ positive cells. The CD3 epsilon complex mediates signal transduction. It plays a major role in signaling during antigen recognition, leading to T cell activation. The TCR/CD3E complex of T lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3 epsilon is expressed on all T cells of all mouse strains.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
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ID gène
- 397455
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UniProt
- Q7YRN2
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Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
Antigène
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