IL-3 anticorps

N° du produit ABIN371622

Cet anticorps anti-IL-3 est un anticorps Rat Monoclonal détectant IL-3 dans FACS, IF, EIA et ELISA (Capture). Adapté pour Souris.

Aperçu rapide pour IL-3 anticorps (ABIN371622)

Antigène: IL-3 (Interleukin 3 (IL-3))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-3 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA), ELISA (Capture)

Clone: MP2-8F8

Détail du produit anti-IL-3 anticorps

Specificité: This antibody is specific to Mouse Interleukin-3/IL-3. (Ref.1-3)

Attributs du produit: Synonyms: IL-3, Multipotential colony-stimulating factor, Hematopoietic growth factor,P-cell-stimulating factor, MCGF, Mast cell growth factor

Purification: Purified

Immunogène: COS-expressed recombinant mouse IL-3.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: Useful useful as a Capture antibody in a Sandwich ELISA for quantifying Mouse IL-3protein levels. (Ref.1-5) This antibody should be paired with purified recombinant mouseIL-3 as the standard. Immunofluorescence/Flow Cytometry: This antibody is useful for intracytoplasmic stainingand flow cytometric analysis to identify and enumerate IL-3-positive cells within mixed cellpopulations. Recombinant mouse IL-3 (Cat#ABIN371622) should be used as a SpecificityControl.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate buffered saline, pH 8.2 without preservatives or amine-containing buffer salts.

Agent conservateur: Without preservative

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IL-3

Antigène: IL-3 (Interleukin 3 (IL-3))

Autre désignation: Interleukin-3 / IL3

Sujet: The pleiotropic IL3 (Interleukin 3) is a 15 kDa cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL3 acts in hematopoiesis by controlling the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and the monocytes/macrophages. It induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes and is expressed by activated T cells, mast cells, and natural killer cells. IL3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL3 has also been shown to protect mast cells from undergoing apoptosis.Synonyms: Hematopoietic growth factor, IL-3, MCGF, Mast cell growth factor, Multipotential colony-stimulating factor, P-cell-stimulating factor

ID gène: 16187

UniProt: P01586

Pathways: Signalistation JAK/STAT, Regulation of Carbohydrate Metabolic Process, Autophagy