YWHAB anticorps (C-Term)

N° du produit ABIN372584

L’anticorps anti-YWHAB Polyclonal produit chez le Lapin a été validé pour WB. Il convient pour la détection de YWHAB dans des échantillons provenant de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Xenopus laevis, Poulet et Primate. }

Aperçu rapide pour YWHAB anticorps (C-Term) (ABIN372584)

Antigène: YWHAB (14-3-3 alpha + beta (YWHAB))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Xenopus laevis, Poulet, Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YWHAB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-YWHAB anticorps

Épitope: C-Term

Specificité: Specific for the ~29k 14-3-3 protein. Immunolabeling of the 14-3-3 protein band is completely blocked by pre-adsorption of the antibody with the C-terminal peptide that was used to generate the antibody.

Réactivité croisée (Details): Species reactivity (expected):Human, Bovine, Canine, Chicken, Mouse, non-Human Primates, Xenopus and Zebrafish.
Species reactivity (tested):Rat.

Purification: Affinity Chromatography.

Immunogène: Peptide corresponding to amino acid residues from the C-terminal region of 14-3-3 protein, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur YWHAB

Antigène: YWHAB (14-3-3 alpha + beta (YWHAB))

Autre désignation: 14-3-3 Protein beta/alpha

Sujet: 14-3-3 proteins are a family of highly conserved proteins that appear to have multiple roles in cell signaling (Bridges and Moorhead, 2005). The proteins are abundantly expressed in the brain and have been detected in the cerebrospinal fluid of patients with different neurological disorders (Berg et al., 2003). 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine or threonine residues and regulate the functions of these binding partners by a number of different mechanisms (Silhan et al., 2004, Dougherty and Morrison, 2004). The 14-3-3 proteins affect a diverse array of cellular processes including the cell cycle and transcription, signal transduction and intracellular trafficking.Synonyms: KCIP-1, Protein 1054, Protein kinase C inhibitor protein 1, YWHAB

ID gène: 56011

NCBI Accession: NP_062250

UniProt: P35213

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location