ELK1 anticorps (pSer383)

N° du produit ABIN372618

Détail du produit anti-ELK1 anticorps

Antigène: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Épitope: pSer383

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Non-Human Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELK1 est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific for ~46k Elk-1 phosphorylated at Ser383. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.

Réactivité croisée (Details): Species reactivity (expected):Human, Canine, Mouse, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat.

Purification: Sequential Chromatography on phospho- and dephosphopeptide affinity columns.

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser383 of human Elk-1.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur ELK1

Antigène: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Autre désignation: ELK1 (ELK1 Produits)

Synonymes: anticorps Elk-1, anticorps Xelk, anticorps Xelk-1, anticorps elk-1, anticorps elk1, anticorps ELK1, ETS transcription factor, anticorps ELK1, member of ETS oncogene family, anticorps ETS domain-containing protein Elk-1, anticorps ELK1, member of ETS oncogene family S homeolog, anticorps ELK1, anticorps Elk1, anticorps Tsp_02690, anticorps elk1, anticorps elk1.S

Sujet: Elk-1 is a transcription factor involved in mediating gene transcription in response to growth factors (Hill and Treisman, 1995). Elk-1 is thought to be phosphorylated by MAP kinase at Ser383 and phosphorylation at this site is essential for the transcriptional activity of Elk-1 (Li et al., 2003). Phosphorylation of Elk-1 has also been implicated in synaptic plasticity in the adult hippocampus (Thiels et al., 2002).Synonyms: ETS domain-containing protein Elk-1, Elk-1

ID gène: 2002

NCBI Accession: NP_001107595

UniProt: P19419

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling