RPS6KA3 anticorps (C-Term)

N° du produit ABIN372713

L’anticorps anti-RPS6KA3 Polyclonal Lapin est utilisé pour la détection de RPS6KA3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien et Poulet. Il a été validé pour WB.

Aperçu rapide pour RPS6KA3 anticorps (C-Term) (ABIN372713)

Antigène: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS6KA3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RPS6KA3 anticorps

Épitope: C-Term

Specificité: This antibody recognizes the ~90k RSK2 protein.

Réactivité croisée (Details): Species reactivity (expected):Bovine, Canine, Chicken, Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography.

Immunogène: Peptide corresponding to amino acid residues from the C-terminal region of rat RSK2, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at-20 °C.

Détails sur RPS6KA3

Antigène: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Autre désignation: RPS6KA3 / RSK2

Sujet: The p90 Ribosomal S6 kinases (RSK1-4) are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006).Synonyms: ISPK-1, ISPK1, MAPKAPK-1b, MAPKAPK1, RSK-2, Ribosomal S6 kinase 2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, p90RSK3

ID gène: 6197

NCBI Accession: NP_004577

UniProt: P51812

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades