OGG1 anticorps (Internal Region)

N° du produit ABIN372767

Détail du produit anti-OGG1 anticorps

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp OGG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: Recognizes 8-oxoguanine DNA Glycosylase Homolog 1 (OGG1).

Réactivité croisée (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human, Rat.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide (C-HPKTSQAKGPSPLANK) from an Internal region of Mouse OGG1.

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/28000. Western Blot: 0.1-0.3 μg/mL. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris Saline Buffer, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur OGG1

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Autre désignation: OGG1 (OGG1 Produits)

Synonymes: anticorps OGG1, anticorps zgc:158858, anticorps 8-oxoguanine-DNA glycosylase 1, anticorps ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1, anticorps ATOGG1, anticorps F8K7.14, anticorps F8K7_14, anticorps 19.m02329, anticorps DDBDRAFT_0184479, anticorps DDBDRAFT_0233024, anticorps DDB_0184479, anticorps DDB_0233024, anticorps ogg1, anticorps Tb04.1H19.930, anticorps HMMH, anticorps HOGG1, anticorps MUTM, anticorps OGH1, anticorps Mmh, anticorps 8-oxoguanine DNA glycosylase, anticorps 8-oxoguanine DNA glycosylase L homeolog, anticorps 8-oxoguanine-DNA glycosylase 1, anticorps 8-OXOGUANINE DNA GLYCOSYLASE, anticorps putative 8-oxoguanine DNA glycosylase, anticorps 8-oxoguanine DNA-glycosylase, anticorps N-glycosylase/DNA lyase OGG1, anticorps 8-oxoguanine DNA-glycosylase 1, anticorps OGG1, anticorps ogg1.L, anticorps ogg1, anticorps ECU08_0770, anticorps CA_C2707, anticorps BBOV_I004290, anticorps Smp_074010.1, anticorps LOC9329243, anticorps Tb927.4.2480, anticorps Ogg1

Sujet: The Ogg1 gene encodes a DNA repair enzyme (N glycosylase/DNA lyase) that incises DNA at 8 oxoG residues. N glycosylase/DNA lyase excises 7,8 dihydro 8 oxoguanine and 2,6 diamino 4 hydroxy 5 N methylformamidopyrimidine (FAPY) from damaged DNA. N glycosylase/DNA lyase has a beta lyase activity that nicks DNA 3' to the lesion. Alternative splicing of the C terminal region of the Ogg1 gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N terminal region in common. Many alternative splice variants for this gene have been described, but the full length nature for every variant has not been determined. The N terminus of this gene contains a mitochondrial targetting signal, essential for mitochondrial localization.Synonyms: MMH, MUTM, N-glycosylase/DNA lyase, OGH1

ID gène: 81528

NCBI Accession: NP_110497

UniProt: O70249

Pathways: Réparation de l'ADN