Reticulon 4 anticorps (N-Term)

N° du produit ABIN372912

Cet anticorps anti-Reticulon 4 est un anticorps Lapin Polyclonal détectant Reticulon 4 dans WB, IHC (p) et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Reticulon 4 anticorps (N-Term) (ABIN372912)

Antigène: Reticulon 4 (RTN4)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Reticulon 4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Reticulon 4 anticorps

Épitope: N-Term

Specificité: This antibody reacts to Neuroendocrine-specific Protein C (RTN4/NOGO).

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide - KLH conjugated corresponding to 23 amino acids from near the amino terminus of Human NOGO-A.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5-1.0 μg/mL. Immunohistochemistry on Paraffin Sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Reticulon 4

Antigène: Reticulon 4 (RTN4)

Autre désignation: Reticulon-4 / RTN4

Sujet: Adult mammalian axon regeneration is generally successful in the peripheral nervous system but poor in the central nervous system. Inhibition results from physical barriers imposed by glial scars, a lack of neurotrophic factors, and growth inhibitory molecules associated with myelin, the insulating axon sheath. These molecules include NI35, myelin associated glycoprotein, and Nogo (Neurite Outgrowth Inhibitor). Nogo is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in adults.Synonyms: Foocen, KIAA0886, NOGO, NSP, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, Reticulon-5

ID gène: 57142

NCBI Accession: NP_008939

UniProt: Q9NQC3

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome