CSK anticorps (C-Term)
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- Antigène Voir toutes CSK Anticorps
- CSK (C-Src tyrosine Kinase (CSK))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CSK est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Séquence
- C-EQLEHIKTHE LHL
- Specificité
- This antibody detects Tyrosine-Protein Kinase CSK at C-term.
- Réactivité croisée (Details)
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Species reactivity (expected):Canine (Dog), Cow.
Species reactivity (tested):Human, Mouse and Rat. - Purification
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- Immunogène
- Peptide from the C Terminus of the protein sequence according to NP_004374.1, NP_001120662.1 Genename: 1445
- Top Product
- Discover our top product CSK Anticorps primaire
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- Indications d'application
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Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 50 kDa band observed in Jurkat lysate (predicted MW of50.0 kDa according to NP_004374.1). Immunohistochemistry: 0.1-0.3 μg/mL. In paraffin embedded human tonsil, strong stainingof germinal centre cells and less intense labelling in the interfollicular area.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CSK (C-Src tyrosine Kinase (CSK))
- Autre désignation
- CSK (CSK Produits)
- Synonymes
- anticorps AW212630, anticorps C-terminal Src kinase, anticorps c-src tyrosine kinase, anticorps CSK, non-receptor tyrosine kinase, anticorps CSK, anticorps Csk
- Sujet
- C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).Synonyms: C-SRC kinase, Protein-tyrosine kinase CYL, Tyrosine-protein kinase CSK
- ID gène
- 1445
- NCBI Accession
- NP_004374
- UniProt
- P41240
- Pathways
- TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
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