HNF4A anticorps (N-Term)

N° du produit ABIN374541

Détail du produit anti-HNF4A anticorps

Antigène: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Épitope: N-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF4A est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to HNF-4-alpha. This antibody is expected to recognise the reported isoforms a, b and c.

Réactivité croisée (Details): Species reactivity (expected):Canine, Porcine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence RLSKTLVDMDMADY-C, from the N Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HNF4A

Antigène: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Autre désignation: HNF4 alpha / TCF14 (HNF4A Produits)

Synonymes: anticorps HNF4A, anticorps HNF4alpha, anticorps CG9310, anticorps DmHNF4, anticorps Dmel\\CG9310, anticorps HNF-4, anticorps HNF-4(D), anticorps HNF4, anticorps Hnf-4, anticorps Hnf-4h, anticorps NR2A4, anticorps dHNF-4, anticorps dHNF4, anticorps Hnf4, anticorps Hnf4alpha, anticorps MODY1, anticorps Nr2a1, anticorps Tcf14, anticorps HNF4a7, anticorps HNF4a8, anticorps HNF4a9, anticorps MODY, anticorps NR2A1, anticorps NR2A21, anticorps TCF, anticorps TCF14, anticorps HNF-4alpha, anticorps fb58h09, anticorps id:ibd1279, anticorps wu:fb58h09, anticorps hnf4, anticorps nr2a1, anticorps hepatocyte nuclear factor 4 alpha, anticorps Hepatocyte nuclear factor 4, anticorps hepatic nuclear factor 4, alpha, anticorps hepatocyte nuclear factor 4, alpha, anticorps hepatocyte nuclear factor 4 alpha S homeolog, anticorps HNF4A, anticorps hnf4a, anticorps Hnf4, anticorps Hnf4a, anticorps hnf4a.S

Sujet: The protein encoded by the HNF4 gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin dependent diabetes mellitus type I. At least three different transcript variants encoding three different isoforms have been found for this gene.Synonyms: HNF4, HNF4A, Hepatocyte nuclear factor 4-alpha, NR2A1, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, Transcription factor HNF-4

ID gène: 3172

NCBI Accession: NP_000448

UniProt: P41235

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process