PDE4D anticorps (C-Term)

N° du produit ABIN374635

Détail du produit anti-PDE4D anticorps

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4D est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: QPEACVIDDR SPDT

Specificité: This antibody detects PDE4D at C-term and is expected to recognize all reported isoforms.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the C-Terminus of the protein sequence according to NP_001098101.1, NP_006194.2, NP_001159371.1. Genename: PDE4D

Information d'application

Indications d'application: Peptide ELISA: 1/128000. Western Blot. : 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PDE4D

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Autre désignation: PDE4D (PDE4D Produits)

Synonymes: anticorps ACRDYS2, anticorps DPDE3, anticorps HSPDE4D, anticorps PDE43, anticorps PDE4DN2, anticorps STRK1, anticorps CMYA2, anticorps MMGL, anticorps 9630011N22Rik, anticorps Dpde3, anticorps 4732458A06Rik, anticorps 9430063L05Rik, anticorps C87016, anticorps D130016K21Rik, anticorps D3Bwg1078e, anticorps Usmg4, anticorps mKIAA0454, anticorps si:dkey-190g11.2, anticorps phosphodiesterase 4D, anticorps phosphodiesterase 4D interacting protein, anticorps phosphodiesterase 4D, cAMP specific, anticorps phosphodiesterase 4D, cAMP-specific, anticorps phosphodiesterase 4D interacting protein (myomegalin), anticorps PDE4D, anticorps PDE4DIP, anticorps pde4d, anticorps Pde4dip, anticorps Pde4d

Sujet: Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE4 enzyme belongs to a family of cAMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cAMP. Four genes (4A, 4B, 4C, and 4D) encode around 20 distinct isoform members of the PDE4 family. Each isoform is characterized by a unique N-terminal region.Synonyms: 5'-cyclic phosphodiesterase 4D, DPDE3, EC=3.1.4.17, PDE43, PDE4D, cAMP-specific 3'

ID gène: 5144

NCBI Accession: NP_001098101

UniProt: Q08499

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling