PDE4D anticorps (C-Term)

N° du produit ABIN374635

Cet anticorps Chèvre Polyclonal détecte spécifiquement PDE4D dans WB et EIA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour PDE4D anticorps (C-Term) (ABIN374635)

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Reactivité: Humain, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4D est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PDE4D anticorps

Épitope: C-Term

Séquence: QPEACVIDDR SPDT

Specificité: This antibody detects PDE4D at C-term and is expected to recognize all reported isoforms.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the C-Terminus of the protein sequence according to NP_001098101.1, NP_006194.2, NP_001159371.1. Genename: PDE4D

Information d'application

Indications d'application: Peptide ELISA: 1/128000. Western Blot. : 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PDE4D

Antigène: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Autre désignation: PDE4D

Sujet: Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE4 enzyme belongs to a family of cAMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cAMP. Four genes (4A, 4B, 4C, and 4D) encode around 20 distinct isoform members of the PDE4 family. Each isoform is characterized by a unique N-terminal region.Synonyms: 5'-cyclic phosphodiesterase 4D, DPDE3, EC=3.1.4.17, PDE43, PDE4D, cAMP-specific 3'

ID gène: 5144

NCBI Accession: NP_001098101

UniProt: Q08499

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling