Stathmin 1 anticorps (C-Term)

N° du produit ABIN374648

Détail du produit anti-Stathmin 1 anticorps

Antigène: Stathmin 1 (STMN1)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Stathmin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody is expected to cross-react with isoform 1a (NP_005554.1, NP_981944.1, NP_981946.1) only. The three reported isoforms (NP_005554.1, NP_981944.1 and NP_981946.1) represent identical protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide (C-KNKESKDPADETEAD) from C-terminus of Human STMN1 (NP_005554.1, NP_981944.1, NP_981946.1)

Information d'application

Indications d'application: ELISA: 1/1000. Western Blot: 1-3 μg/mL. Immunohistochemistry on Paraffin Sections: 3.75 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Stathmin 1 (ABIN374648)

Watabe-Rudolph, Song, Lausser, Schnack, Begus-Nahrmann, Scheithauer, Rettinger, Otto, Tumani, Thal, Attems, Jellinger, Kestler, von Arnim, Rudolph: "Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease." dans: Neurology, Vol. 78, Issue 8, pp. 569-77, (2012) (PubMed).

Wallukat, Muñoz Saravia, Haberland, Bartel, Araujo, Valda, Duchen, Diaz Ramirez, Borges, Schimke: "Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients." dans: Journal of the American College of Cardiology, Vol. 55, Issue 5, pp. 463-8, (2010) (PubMed).

Détails sur Stathmin 1

Antigène: Stathmin 1 (STMN1)

Autre désignation: Stathmin / STMN1 (STMN1 Produits)

Synonymes: anticorps C1orf215, anticorps LAP18, anticorps Lag, anticorps OP18, anticorps PP17, anticorps PP19, anticorps PR22, anticorps SMN, anticorps 19k, anticorps Lap18, anticorps Op18, anticorps P18, anticorps P19, anticorps Pig, anticorps Pp17, anticorps Pp18, anticorps Pp19, anticorps Pr22, anticorps Smn, anticorps prosolin, anticorps op18, anticorps stathmin, anticorps stmn1, anticorps stmn1a, anticorps lag, anticorps lap18, anticorps pp17, anticorps pp19, anticorps pr22, anticorps smn, anticorps fj43c10, anticorps wu:fj38b07, anticorps wu:fj43c10, anticorps zgc:110159, anticorps cb959, anticorps wu:fb14e04, anticorps zgc:136942, anticorps stmn1-a, anticorps stmn1b, anticorps xo35, anticorps stathmin 1, anticorps stathmin 1 S homeolog, anticorps stathmin 1b, anticorps stathmin 1a, anticorps stathmin-like, anticorps stathmin, anticorps stathmin 1 L homeolog, anticorps STMN1, anticorps Stmn1, anticorps stmn1.S, anticorps stmn1, anticorps stmn1b, anticorps stmn1a, anticorps LOC100229194, anticorps stmn1.L

Sujet: STMN1 is a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Alternatively spliced transcript variants encoding the same protein have been identified.Synonyms: LAP18, Leukemia-associated phosphoprotein p18, Metablastin, OP18, Oncoprotein 18, Op18, Phosphoprotein p19, Prosolin, Protein Pr22, pp17, pp19

Poids moléculaire: 17.3kDa (NP_005554.1, NP_981944.1 and NP_981946.1).

ID gène: 3925, 9606

UniProt: P16949

Pathways: Signalisation MAPK, Dynamique des Microtubules