HSD11B1 anticorps (C-Term)

N° du produit ABIN374673

Détail du produit anti-HSD11B1 anticorps

Antigène: HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD11B1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to HSD3B1.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-DRHKETLKSKTQ, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/128000. Western Blot: 0.01 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HSD11B1

Antigène: HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

Autre désignation: 3-beta-HSD1 / HSD3B1 (HSD11B1 Produits)

Synonymes: anticorps 11-DH, anticorps 11-beta-HSD1, anticorps CORTRD2, anticorps HDL, anticorps HSD11, anticorps HSD11B, anticorps HSD11L, anticorps SDR26C1, anticorps hsd11, anticorps hsd11b, anticorps LRRGT00065, anticorps hydroxysteroid 11-beta dehydrogenase 1, anticorps hydroxysteroid (11-beta) dehydrogenase 1b, anticorps hydroxysteroid (11-beta) dehydrogenase 1 L homeolog, anticorps HSD11B1, anticorps HSD11B1b, anticorps hsd11b1.L, anticorps Hsd11b1

Sujet: HSD3B1 (3-beta hydroxysteroid dehydrogenase) is a bifunctional enzyme that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. There are two HSD3B1 proteins, type I and type II. Expressed by different genes, they function in different areas of the body. HSD3B1 has been shown to be a highly specific and sensitive trophoblast-associated marker (Mao et. al).Synonyms: 3-beta-hydroxysteroid dehydrogenase, Delta 5-->4-isomerase type 1, Trophoblast Marker

ID gène: 3283

NCBI Accession: NP_000853

UniProt: P14060

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process