VANGL2 anticorps (Internal Region)

N° du produit ABIN374805

Détail du produit anti-VANGL2 anticorps

Antigène: VANGL2 (Vang-Like 2 (VANGL2))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp VANGL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-QKYLRTTKQQ PYH

Specificité: This antibody detects Vang-like protein 2 (VANGL2).

Réactivité croisée (Details): Species reactivity (expected):Cow, ZebrafishSpecies reactivity (tested):Human, Mouse

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_065068.1 Genename: VANGL2

Information d'application

Indications d'application: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx 55 kDa band observed in Human Lung and Mouse Brainlysates (calculated MW of 59.5 kDa according to NP_065068.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur VANGL2

Antigène: VANGL2 (Vang-Like 2 (VANGL2))

Autre désignation: Vang-Like Protein 2 (VANGL2) (VANGL2 Produits)

Synonymes: anticorps Strabismus, anticorps lpp1, anticorps ltap, anticorps stb1, anticorps stbm, anticorps stbm1, anticorps VANGL2, anticorps LPP1, anticorps LTAP, anticorps STB1, anticorps STBM, anticorps STBM1, anticorps C530001F03Rik, anticorps Lp, anticorps Lpp1, anticorps Ltap, anticorps Vang1l2, anticorps loop-tail, anticorps ska17, anticorps ska, anticorps strabismus, anticorps tri, anticorps vang, anticorps vangl2, anticorps vangl2b, anticorps vangl2a, anticorps VANGL planar cell polarity protein 2, anticorps vang-like 2 (van gogh, Drosophila), anticorps VANGL planar cell polarity protein 2 S homeolog, anticorps VANGL planar cell polarity protein 2 L homeolog, anticorps vangl2, anticorps VANGL2, anticorps Vangl2, anticorps vangl2.S, anticorps vangl2.L

Sujet: VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.Synonyms: KIAA1215, Loop-tail protein 1 homolog, STB1, Strabismus 1, Van Gogh-like protein 2

ID gène: 57216, 9606

UniProt: Q9ULK5

Pathways: Signalisation WNT, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization