GALNS anticorps (Internal Region)

N° du produit ABIN374878

Cet anticorps Chèvre Polyclonal détecte spécifiquement GALNS dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour GALNS anticorps (Internal Region) (ABIN374878)

Antigène: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GALNS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GALNS anticorps

Épitope: Internal Region

Séquence: C-TTHNLEDHTK LP

Specificité: This antibody detects GALNS.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_000503.1 Genename: GALNS

Information d'application

Indications d'application: Peptide ELISA: limit dilution 1: 64000. Western blot: 0.01-0.03 μg/mL. Approx 60 kDa band observed in Human Bone Marrow andPlacenta lysates (calculated MW of 58.0 kDa according to NP_000503.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur GALNS

Antigène: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Autre désignation: GALNS

Sujet: GALNS (N-acetylgalactosamine-6-sulfatase) is a lysosomal exohydrolase which catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.Synonyms: Chondroitinase, Chondroitinsulfatase, EC=3.1.6.4, GalNAc6S sulfatase, Galactose-6-sulfate sulfatase, N-acetylgalactosamine-6-sulfatase, N-acetylgalactosamine-6-sulfate sulfatase

ID gène: 2588

NCBI Accession: NP_000503

UniProt: P34059

Pathways: Glycosaminoglycan Metabolic Process