FZD7 anticorps (C-Term)
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- Antigène Voir toutes FZD7 Anticorps
- FZD7 (Frizzled Family Receptor 7 (FZD7))
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Épitope
- C-Term
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Reactivité
- Humain, Souris
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FZD7 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- C-RFYHRLSHSS KGET
- Specificité
- This antibody recognizes Frizzled 7 (C-term).
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - Purification
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- Immunogène
- Peptide with sequence C-RFYHRLSHSSKGET from the C Terminus of Human FZD7 (NP_003498.1).
- Top Product
- Discover our top product FZD7 Anticorps primaire
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- Indications d'application
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Peptide ELISA: Detection Limit Dilution: 1/64000. Western Blot: 0.3-1 μg/mL. Approx 60 kDa band observed in lysates of cell lines HEK293 andHepG2 (calculated MW of 63.0 kDa according to NP_003498.1). Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- Autre désignation
- FZD7 / Frizzled-7 (FZD7 Produits)
- Synonymes
- anticorps FzE3, anticorps Fz-7, anticorps Xfz7, anticorps frizzled-7, anticorps frizzled7, anticorps frz-7, anticorps frz7, anticorps fz7, anticorps fzd7-a, anticorps fzd7-b, anticorps fze3, anticorps Fz7, anticorps cFz-7, anticorps fb38g02, anticorps fc44b09, anticorps fz13, anticorps fz7a, anticorps fz7b, anticorps wu:fb38g02, anticorps wu:fc44b09, anticorps zg13, anticorps frizzled class receptor 7, anticorps frizzled class receptor 7 L homeolog, anticorps frizzled class receptor 7b, anticorps FZD7, anticorps fzd7.L, anticorps fzd7, anticorps Fzd7, anticorps fzd7b
- Sujet
- Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The Frizzled 7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Frizzled family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. Frizzled 7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. Frizzled 7 expression has been reported in brain, gastrointestinal tract, heart, fetal kidney, fetal lung, placenta, skeletal muscle, and various cancers. ESTs have been isolated from a wide variety of normal and cancer libraries.Synonyms: Fz-7, mFz7
- ID gène
- 8324
- NCBI Accession
- NP_003498
- UniProt
- O75084
- Pathways
- Signalisation WNT, Stem Cell Maintenance
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