IGFBP6 anticorps (Internal Region)

N° du produit ABIN374965

Détail du produit anti-IGFBP6 anticorps

Antigène: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Épitope: Internal Region

Reactivité: Humain, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IGFBP6 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to IGFBP6.

Réactivité croisée (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-RPQDVNRRDQQRNP, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IGFBP6

Antigène: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Autre désignation: IGFBP6 (IGFBP6 Produits)

Synonymes: anticorps IBP6, anticorps IGFBP-6, anticorps IGF-BP6, anticorps RBP6A, anticorps IGFBP6, anticorps igfbp6, anticorps insulin like growth factor binding protein 6, anticorps insulin-like growth factor binding protein 6, anticorps IGFBP6, anticorps Igfbp6, anticorps IGFBP-6, anticorps igfbp6

Sujet: IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis. IGFBP6 has been shown to be imported into the nuclei of rhabdomyosarcoma and HEK-293 cells. This is mediated by a NLS sequence that bears limited homology to those found in IGFBP-3 and -5. Deletion of the NLS segment abolishes the pro-apoptotic effect of IGFBP6.Synonyms: IBP-6, IBP6, IGF-binding protein 6, IGFBP-6, Insulin-like growth factor-binding protein 6

ID gène: 3489, 9606

UniProt: P24592

Pathways: Signalisation WNT, Myometrial Relaxation and Contraction