IGFBP6 anticorps (Internal Region)

N° du produit ABIN374965

Cet anticorps Chèvre Polyclonal détecte spécifiquement IGFBP6 dans WB. Il présente une réactivité avec des échantillons de Humain et Boeuf (Vache).

Aperçu rapide pour IGFBP6 anticorps (Internal Region) (ABIN374965)

Antigène: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Reactivité: Humain, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IGFBP6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IGFBP6 anticorps

Épitope: Internal Region

Specificité: This antibody reacts to IGFBP6.

Réactivité croisée (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-RPQDVNRRDQQRNP, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IGFBP6

Antigène: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Autre désignation: IGFBP6

Sujet: IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis. IGFBP6 has been shown to be imported into the nuclei of rhabdomyosarcoma and HEK-293 cells. This is mediated by a NLS sequence that bears limited homology to those found in IGFBP-3 and -5. Deletion of the NLS segment abolishes the pro-apoptotic effect of IGFBP6.Synonyms: IBP-6, IBP6, IGF-binding protein 6, IGFBP-6, Insulin-like growth factor-binding protein 6

ID gène: 3489, 9606

UniProt: P24592

Pathways: Signalisation WNT, Myometrial Relaxation and Contraction