CD19 anticorps (APC)
Aperçu rapide pour CD19 anticorps (APC) (ABIN375780)
Antigène
Voir toutes CD19 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Mouse CD19, Mr 95 kDa
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Attributs du produit
- Mouse Anti-Mouse CD19-APC
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Purification
- Purified
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Immunogène
- CD19+ mouse pre-B cell line 300.19
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Isotype
- IgA
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Indications d'application
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- Applications: FC - Quality tested , IP - Reported in literature , Activ - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells APC/CY5.5 and APC/CY7 conjugates 0.3 g/106 cells PE, APC, SPRD, and PE/CY5.5 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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Volume d'échantillon
- 1 mL
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. -
Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C
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- CD19 (CD19 Molecule (CD19))
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Autre désignation
- CD19
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Sujet
- CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e., B220 + /CD43 + /HSA + ) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM + cells of both B-1 and B-2 lineages are CD19 +, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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