CD44 anticorps (APC)

N° du produit ABIN375814

Cet anticorps Souris Monoclonal détecte spécifiquement CD44 dans FACS, IHC et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CD44 anticorps (APC) (ABIN375814)

Antigène: CD44

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est conjugé à/à la APC

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: F10-44-2

Détail du produit anti-CD44 anticorps (APC)

Specificité: Human/Ma's Night Monkey CD44, Mr 80 - 95 kDa

Attributs du produit: Mouse Anti-Human CD44-APC

Purification: Purified

Immunogène: Purified T cells from human lymph nodes

Isotype: IgG2a

Information d'application

Indications d'application: Working Dilution:
10 µL/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: CD44, also known as phagocytic glycoprotein-1 (Pgp-1) and the receptor for hyaluronate, exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing and adhesion during hematopoiesis and lymphocyte activation.

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling