CD74 anticorps

N° du produit ABIN376401

Cet anticorps anti-CD74 Monoclonal Souris (Clone LN2) (ABIN376401) détecte spécifiquement CD74 dans FACS, WB, IP, IHC (p), ICC, IHC (fro) et BR. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD74 anticorps (ABIN376401)

Antigène: CD74 (HLA-DR-gamma (CD74))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD74 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Clone: LN2

Détail du produit anti-CD74 anticorps

Fonction: Mouse Anti-Human CD74-LE/AF

Specificité: Human CD74, Mr 41, 35, 33 kDa

Attributs du produit: Low Endotoxin/Azide Free Anti-Human CD74 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: Cell line SU-DHL-4 nuclei

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur CD74

Antigène: CD74 (HLA-DR-gamma (CD74))

Autre désignation: CD74

Sujet: CD74 represents a type II integral membrane protein known as MHC Class II-associated invariant chain (Mr 43, 41, 35, 33 kDa). It is moderately expressed on B cells, and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of Class II molecules on the cell surface.

ID gène: 972

UniProt: P04233

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints