ITGA2 anticorps

N° du produit ABIN376997

L’anticorps anti-ITGA2 Monoclonal Souris est utilisé pour la détection de ITGA2 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour ITGA2 anticorps (ABIN376997)

Antigène: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA2 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: HAS-4

Détail du produit anti-ITGA2 anticorps

Specificité: Human CD49b, Mr 160 kDa

Attributs du produit: Mouse Anti-Human CD49b-UNLB

Purification: Purified

Immunogène: Human keratinocytes

Isotype: IgG2a

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Agent conservateur: Without preservative

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Détails sur ITGA2

Antigène: ITGA2 (Integrin alpha 2 (ITGA2))

Autre désignation: CD49b

Sujet: CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin α 2 chain. CD49b associates noncovalently with CD29, the integrin β 1 subunit, to form the heterodimer integrin a2b1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts and long-term cultured T cells. CD49b/CD29 mediates the Mg ++ - dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during would healing.

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex