Caspase 3 anticorps

N° du produit ABIN379634

Cet anticorps Lapin Polyclonal détecte spécifiquement Caspase 3 dans IHC et IHC (p). Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Singe, Porc, Mouton et Hamster.

Aperçu rapide pour Caspase 3 anticorps (ABIN379634)

Antigène: Caspase 3 (CASP3)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Singe, Porc, Mouton, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 3 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Caspase 3 anticorps

Specificité: Reacts with active form of caspase 3 (17 kD protein). Caspase 3 is a member of the interleukin-1 beta-converting enzyme family. Caspase 3 is though to be associated with induction of apoptosis. Caspase 3 is synthesized as inactive 32 kD proenzyme and is processed during apoptosis generating two subunits of 17 kD and 12 kD. Caspase 3 stains the epithelial cells of skin, renal proximal tubules and collecting ducts. This antibody cross reacts with mouse, rat, monkey, rabbit, hamster, cow, sheep, pig and dog.

Purification: Ig fraction

Immunogène: Recombinant full-length human Caspase 3 protein.

Type of Immunogen: Recombinant protein

Information d'application

Indications d'application: Approved: IHC, IHC-P (1:50 - 1:100)

Usage: FFPE tissue sections require high temperature antigen unmasking with 10 mM citrate buffer,  pH 6.0 prior to immunostaining.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Antiserum, sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur Caspase 3

Antigène: Caspase 3 (CASP3)

Autre désignation: CASP3 / Caspase 3

Sujet: Name/Gene ID: CASP3
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama

ID gène: 836

Pathways: Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation