Angiotensin I Converting Enzyme 1 anticorps

N° du produit ABIN379980

Cet anticorps anti-Angiotensin I Converting Enzyme 1 Monoclonal Souris (Clone CG2) (ABIN379980) détecte spécifiquement Angiotensin I Converting Enzyme 1 dans IHC et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Angiotensin I Converting Enzyme 1 anticorps (ABIN379980)

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Angiotensin I Converting Enzyme 1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CG2

Détail du produit anti-Angiotensin I Converting Enzyme 1 anticorps

Specificité: The antigen is CD143, the epitope is apparently localized in the N-terminal portion of the protein. Antigen distribution: Tissue sections: Topographically the degree of expression correlates with the proportion of smooth muscle cells and elastic fibres of the vessel wall. ACE is predominantely expressed by small muscular arteries and by arterioles, whereas small and large veins do not usually express ACE. However, no ACE could be detected in the endothelial cells of kidney. Constitutively ACE is expressed on endothelial cells in different diseases like hypertension, myocardial infarction, sarcoidosis, diabetes. Specificity: Human: denatured ACE. Other species: not tested.

Purification: Affinity purified

Immunogène: purified ACE from human lung and kidney

Information d'application

Indications d'application: Approved: IHC, IHC-P (1:50)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.5 mL distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.1 % Kathon

Agent conservateur: Kathon CG

Stock: 4 °C

Stockage commentaire: Store at 4°C.

Détails sur Angiotensin I Converting Enzyme 1

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Autre désignation: ACE / DCP1 / CD143

Sujet: Name/Gene ID: ACE
Subfamily: Metallopeptidase M2
Family: Protease

Synonyms: ACE, ACE1, Angiotensin-converting enzyme, CD143, CD143 antigen, Carboxycathepsin, DIPEPTIDYL CARBOXYPEPTIDASE, DCP, Dipeptidyl carboxypeptidase I, ICH, Kininase II, MVCD3, Peptidyl-dipeptidase A, Peptidase P, DCP1, Dipeptidyl carboxypeptidase 1, Testicular ECA

ID gène: 1636

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration