BMPR1A anticorps (N-Term)

N° du produit ABIN388737

Cité dans 1 publication. Cet anticorps anti-BMPR1A Polyclonal Lapin (Clone RB04050) (ABIN388737) détecte spécifiquement BMPR1A dans WB et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour BMPR1A anticorps (N-Term) (ABIN388737)

Antigène: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMPR1A est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB04050

Détail du produit anti-BMPR1A anticorps

Épitope: AA 1-30, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BMPR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BMPR1A.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-BMPR1A (ABIN388737)

Tominaga, Abe, Ueda, Goto, Nakahara, Murakami, Matsubara, Mima, Nagai, Araoka, Kishi, Fukushima, Jishage, Doi: "Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy." dans: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 20109-16, (2011) (PubMed).

Détails sur BMPR1A

Antigène: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Autre désignation: BMPR1A

Sujet: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Poids moléculaire: 60198

ID gène: 657

NCBI Accession: NP_004320

UniProt: P36894

Pathways: Stem Cell Maintenance