BMPR1A anticorps (AA 30-60)
Aperçu rapide pour BMPR1A anticorps (AA 30-60) (ABIN3030186)
Antigène
Voir toutes BMPR1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 30-60
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Fonction
- ALK3 Antibody
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Réactivité croisée (Details)
- Expected species reactivity: Mouse, Rat
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Purification
- Purified
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Immunogène
- A portion of amino acids 30-60 from the human protein was used as the immunogen for this ALK3 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the ALK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the ALK3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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Autre désignation
- ALK3
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Sujet
- The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A/ALK3 and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
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UniProt
- P36894
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Pathways
- Stem Cell Maintenance
Antigène
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