BMPR1A anticorps (N-Term)

N° du produit ABIN388732

Détail du produit anti-BMPR1A anticorps

Antigène: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Épitope: AA 30-60, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMPR1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BMPR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-60 amino acids from the N-terminal region of human BMPR1A.

Clone: RB01766

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-BMPR1A (ABIN388732)

Peng, Mukhopadhyay, Jarrett, Yoshikawa, Kessler: "BMP receptor 1A regulates development of hypothalamic circuits critical for feeding behavior." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 48, pp. 17211-24, (2012) (PubMed).

Kan, Liu, McGuire, Berger, Awatramani, Dymecki, Kessler: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." dans: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, (2009) (PubMed).

Mukhopadhyay, McGuire, Peng, Kessler: "Differential effects of BMP signaling on parvalbumin and somatostatin interneuron differentiation." dans: Development (Cambridge, England), Vol. 136, Issue 15, pp. 2633-42, (2009) (PubMed).

Détails sur BMPR1A

Antigène: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Autre désignation: BMPR1A (BMPR1A Produits)

Synonymes: anticorps 10q23del, anticorps ACVRLK3, anticorps ALK3, anticorps CD292, anticorps SKR5, anticorps 1110037I22Rik, anticorps AU045487, anticorps BMPR-IA, anticorps Bmpr, anticorps BMPR-1, anticorps BRK-1, anticorps BMPR1A, anticorps acvrlk3, anticorps alk-3, anticorps alk3, anticorps cd292, anticorps skr5, anticorps BR1a, anticorps alk3tr, anticorps bmpr1a, anticorps zgc:136731, anticorps wu:fe05b06, anticorps wu:fe06e10, anticorps zgc:92227, anticorps bone morphogenetic protein receptor type 1A, anticorps bone morphogenetic protein receptor, type 1A, anticorps bone morphogenetic protein receptor type 1A S homeolog, anticorps bone morphogenetic protein receptor, type IAa, anticorps bone morphogenetic protein receptor, type IAb, anticorps BMPR1A, anticorps Bmpr1a, anticorps bmpr1a, anticorps bmpr1a.S, anticorps bmpr1aa, anticorps bmpr1ab

Sujet: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Poids moléculaire: 60198

ID gène: 657

NCBI Accession: NP_004320

UniProt: P36894

Pathways: Stem Cell Maintenance