FZD1 anticorps (C-Term)
Aperçu rapide pour FZD1 anticorps (C-Term) (ABIN389235)
Antigène
Voir toutes FZD1 (Fzd1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 504-533, C-Term
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Homologie
- C, M, Rat, X
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This FZD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 504-533 amino acids from the C-terminal region of human FZD1.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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: "Overexpression of FZD1 and CAIX are Associated with Invasion, Metastasis, and Poor-Prognosis of the Pancreatic Ductal Adenocarcinoma." dans: Pathology oncology research : POR, Vol. 24, Issue 4, pp. 899-906, (2018) (PubMed).
: "Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1." dans: PLoS ONE, Vol. 11, Issue 10, pp. e0163277, (2017) (PubMed).
: "Functional and association analysis of frizzled 1 (FZD1) promoter haplotypes with femoral neck geometry." dans: Bone, Vol. 46, Issue 4, pp. 1131-7, (2010) (PubMed).
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: "Overexpression of FZD1 and CAIX are Associated with Invasion, Metastasis, and Poor-Prognosis of the Pancreatic Ductal Adenocarcinoma." dans: Pathology oncology research : POR, Vol. 24, Issue 4, pp. 899-906, (2018) (PubMed).
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- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
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Autre désignation
- FZD1
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Sujet
- Members of the 'frizzled' proten family are 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.The FZD1 transcript is expressed in various tissues.
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Poids moléculaire
- 71158
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ID gène
- 8321
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NCBI Accession
- NP_003496
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UniProt
- Q9UP38
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Pathways
- Signalisation WNT, Asymmetric Protein Localization
Antigène
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