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CDK1 anticorps (pSer39)

Cet anticorps anti-CDK1 est un anticorps Lapin Polyclonal détectant CDK1 dans WB, IHC (p) et DB. Adapté pour Humain.
N° du produit ABIN389538

Aperçu rapide pour CDK1 anticorps (pSer39) (ABIN389538)

Antigène

Voir toutes CDK1 Anticorps
CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivité

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Humain

Hôte

  • 250
  • 75
Lapin

Clonalité

  • 233
  • 92
Polyclonal

Conjugué

  • 172
  • 24
  • 14
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Cet anticorp CDK1 est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Clone

RB7849
  • Épitope

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    • 1
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    • 1
    • 1
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    • 1
    • 1
    • 1
    pSer39

    Homologie

    B, C, M, Rat

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This CDK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S39 of human CDK1.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. IHC-P: 1:50~100. DB: 1:500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Antigène

    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

    Autre désignation

    CDK1

    Sujet

    The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.

    Poids moléculaire

    34095

    ID gène

    983

    NCBI Accession

    NP_001777, NP_203698

    UniProt

    P06493

    Pathways

    Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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