MAPKAP Kinase 2 anticorps (pSer272)

N° du produit ABIN389585

Il existe 1 publication pour ce produit. L’anticorps anti-MAPKAP Kinase 2 Polyclonal Lapin est utilisé pour la détection de MAPKAP Kinase 2 dans des échantillons de Humain. Il a été validé pour IHC (p) et DB.

Aperçu rapide pour MAPKAP Kinase 2 anticorps (pSer272) (ABIN389585)

Antigène: MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKAP Kinase 2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Clone: RB05555

Détail du produit anti-MAPKAP Kinase 2 anticorps

Épitope: pSer272

Homologie: M, Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MAPKAPK2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S272 of human MAPKAPK2.

Isotype: Ig Fraction

Information d'application

Indications d'application: IHC-P: 1:50~100. DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MAPKAP Kinase 2 (ABIN389585)

Xu, Zhou, Xiong, Zou, Deng, Ganaie, Kleiboeker, Peng, Liu, Wang, Ye, Qiu: "Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway." dans: PLoS pathogens, Vol. 13, Issue 3, pp. e1006266, (2017) (PubMed).

Détails sur MAPKAP Kinase 2

Antigène: MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))

Autre désignation: MAPKAPK2

Sujet: This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Poids moléculaire: 45568

ID gène: 9261

NCBI Accession: NP_004750, NP_116584

UniProt: P49137

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades