MAP3K1 anticorps (pThr1383)

N° du produit ABIN389719

Cet anticorps Lapin Polyclonal détecte spécifiquement MAP3K1 dans DB. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour MAP3K1 anticorps (pThr1383) (ABIN389719)

Antigène: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K1 est non-conjugé

Application: Dot Blot (DB)

Clone: RB11308

Détail du produit anti-MAP3K1 anticorps

Épitope: pThr1383

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MAP3K1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1400 of human MAP3K1.

Isotype: IgG

Information d'application

Indications d'application: DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MAP3K1 (ABIN389719)

Craig, Parker, Austin, Barnett, Camenisch: "Involvement of the MEKK1 signaling pathway in the regulation of epicardial cell behavior by hyaluronan." dans: Cellular signalling, Vol. 22, Issue 6, pp. 968-76, (2010) (PubMed).

Mokhtari, Myers, Welsh: "MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells." dans: Diabetes, Vol. 57, Issue 7, pp. 1896-904, (2008) (PubMed).

Détails sur MAP3K1

Antigène: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Autre désignation: MAP3K1

Sujet: Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.

Poids moléculaire: 164470

ID gène: 4214

NCBI Accession: NP_005912

UniProt: Q13233

Pathways: Signalisation MAPK, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades