MMP14 anticorps (N-Term)

N° du produit ABIN390138

Cité dans 2 publications. Cet anticorps anti-MMP14 Polyclonal Lapin (Clone RB02027) (ABIN390138) détecte spécifiquement MMP14 dans WB, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MMP14 anticorps (N-Term) (ABIN390138)

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB02027

Détail du produit anti-MMP14 anticorps

Épitope: AA 145-174, N-Term

Homologie: B, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MMP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the N-terminal region of human MMP14.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:2000. IHC-P: 1:25. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MMP14 (ABIN390138)

Du, Wang, Tan, Li, Huang, Huang, Yang, Zhang, Wang, Huang, Huang: "Nkx2-5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E-Deficient Mice." dans: Journal of the American Heart Association, Vol. 5, Issue 12, (2017) (PubMed).

Zhu, Hong, Tripathi, Sehdev, Belkhiri, El-Rifai: "Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells." dans: Molecular cancer research : MCR, Vol. 11, Issue 1, pp. 86-94, (2013) (PubMed).

Détails sur MMP14

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MMP14

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.

Poids moléculaire: 65894

ID gène: 4323

NCBI Accession: NP_004986

UniProt: P50281

Pathways: Autophagy