MMP14 anticorps (C-Term)

N° du produit ABIN4911994

Cet anticorps Souris Monoclonal détecte spécifiquement MMP14 dans WB, IF, IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MMP14 anticorps (C-Term) (ABIN4911994)

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP14 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 3A6

Détail du produit anti-MMP14 anticorps

Épitope: AA 470-499, C-Term

Fonction: MMP14 (3A6) Monoclonal Antibody

Réactivité croisée: Humain

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This MMP14 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP14.

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin, Sodium azide

Précaution d'utilisation: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MMP14

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MMP14

Sujet:

Synonyms: MMP-14, MMP-X1, MT-MMP, MT1MMP, MTMMP1, WNCHRS, MT1-MMP, MT-MMP 1, Matrix metalloproteinase-14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP14

Background: Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.

ID gène: 4323

UniProt: P50281

Pathways: Autophagy