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HIRA anticorps (AA 431-461)

HIRA Reactivité: Humain WB Hôte: Lapin Polyclonal RB13843 unconjugated
N° du produit ABIN390223
  • Antigène Voir toutes HIRA Anticorps
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    Épitope
    • 15
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 431-461
    Reactivité
    • 43
    • 33
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 50
    • 10
    Lapin
    Clonalité
    • 50
    • 10
    Polyclonal
    Conjugué
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HIRA est non-conjugé
    Application
    • 45
    • 23
    • 13
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    C, M, X
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This HIRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-461 amino acids from the Central region of human HIRA.
    Clone
    RB13843
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HIRA Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    Autre désignation
    HIRA (HIRA Produits)
    Synonymes
    anticorps HIRA, anticorps wu:fb97b07, anticorps wu:fi43b08, anticorps si:ch211-188g24.3, anticorps AA138857, anticorps D16Ertd95e, anticorps N28177, anticorps Tuple1, anticorps DGCR1, anticorps TUP1, anticorps TUPLE1, anticorps dgcr1, anticorps hira-A, anticorps tup1, anticorps tuple1, anticorps homolog of histone chaperone HIRA, anticorps histone cell cycle regulator, anticorps histone cell cycle regulator a, anticorps protein HIRA, anticorps HIR histone cell cycle regulation defective homolog A (S. cerevisiae), anticorps HIRA, anticorps histone cell cycle regulator S homeolog, anticorps histone chaperone HIRA-like protein, anticorps Tuple1/HirA, anticorps HIRA, anticorps hira, anticorps LOC100052845, anticorps LOC100352472, anticorps LOC100407742, anticorps LOC100450459, anticorps LOC100467668, anticorps LOC100581135, anticorps LOC486424, anticorps Hira, anticorps LOC732736, anticorps hira.S
    Sujet
    HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
    Poids moléculaire
    111835
    ID gène
    7290
    NCBI Accession
    NP_003316
    UniProt
    P54198
    Pathways
    Chromatin Binding
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