Kallikrein 5 anticorps (AA 144-174)
Aperçu rapide pour Kallikrein 5 anticorps (AA 144-174) (ABIN390305)
Antigène
Voir toutes Kallikrein 5 (KLK5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 144-174
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This Kallikrein 5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the Central region of human Kallikrein 5.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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: "Loss of ceramide synthase 3 causes lethal skin barrier disruption." dans: Human molecular genetics, Vol. 21, Issue 3, pp. 586-608, (2012) (PubMed).
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- Kallikrein 5 (KLK5)
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Sujet
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.
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Poids moléculaire
- 32020
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ID gène
- 25818
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NCBI Accession
- NP_001070959, NP_001070960, NP_036559
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UniProt
- Q9Y337
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Pathways
- Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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