GNS anticorps (AA 174-203)

N° du produit ABIN390494

L’anticorps Lapin Polyclonal anti-GNS a été validé pour WB et IHC (p). Il convient pour détecter GNS dans des échantillons de Humain.

Aperçu rapide pour GNS anticorps (AA 174-203) (ABIN390494)

Antigène: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19340

Détail du produit anti-GNS anticorps

Épitope: AA 174-203

Homologie: B, M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This GNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the Central region of human GNS.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur GNS

Antigène: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Autre désignation: GNS

Sujet: GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

Poids moléculaire: 62082

ID gène: 2799

NCBI Accession: NP_002067

UniProt: P15586

Pathways: Glycosaminoglycan Metabolic Process