VCP anticorps (C-Term)

N° du produit ABIN390907

Cet anticorps Lapin Polyclonal détecte spécifiquement VCP dans WB, IHC (p) et FACS. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour VCP anticorps (C-Term) (ABIN390907)

Antigène: VCP (Valosin Containing Protein (VCP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VCP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB21276

Détail du produit anti-VCP anticorps

Épitope: AA 726-755, C-Term

Homologie: B, Zf, M, Pig, Rat, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This VCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 726-755 amino acids from the C-terminal region of human VCP.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-VCP (ABIN390907)

Ayaki, Ito, Fukushima, Inoue, Kondo, Ikemoto, Asano, Shodai, Fujita, Fukui, Morino, Nakano, Kusaka, Yamashita, Ihara, Matsumoto, Kawamata, Urushitani, Kawakami, Takahashi: "Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant." dans: Acta neuropathologica communications, Vol. 2, pp. 172, (2015) (PubMed).

Détails sur VCP

Antigène: VCP (Valosin Containing Protein (VCP))

Autre désignation: VCP

Sujet: VCP is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.

Poids moléculaire: 89322

ID gène: 7415

NCBI Accession: NP_009057

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway