RYK anticorps (AA 383-410)
Aperçu rapide pour RYK anticorps (AA 383-410) (ABIN392052)
Antigène
Voir toutes RYK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 383-410
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This RYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-410 amino acids from the Central region of human RYK.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
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Autre désignation
- RYK
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Sujet
- RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
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Poids moléculaire
- 67815
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ID gène
- 6259
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NCBI Accession
- NP_001005861, NP_002949
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UniProt
- P34925
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Pathways
- Signalisation RTK, Signalisation WNT, Regulation of Cell Size
Antigène
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