L’anticorps Lapin Polyclonal anti-PTK6 a été validé pour WB et IHC (p). Il convient pour détecter PTK6 dans des échantillons de Humain. Il y a 2+ publications disponibles.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This BRK (PTK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of human BRK (PTK6).
PTK6
Reactivité: Humain, Cheval
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Xu, Ye, Wu, He, Tan, Xiao, Wu, Yu, Mai, Li, Peng, Huang, Li, Zhang, Zhu, Qin: "Overexpression of PTK6 predicts poor prognosis in bladder cancer patients." dans: Journal of Cancer, Vol. 8, Issue 17, pp. 3464-3473, (2018) (PubMed).
Chen, Ma, Cao, Huang, Zeng, Wen: "Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma." dans: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 317, (2014) (PubMed).
Antigène
PTK6
(PTK6 Protein tyrosine Kinase 6 (PTK6))
Autre désignation
BRK (PTK6)
Sujet
PTK6 is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation.