PTK6 anticorps

N° du produit ABIN969373

Détail du produit anti-PTK6 anticorps

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTK6 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of human PTK6 expressed in E. coli.

Clone: 2H12B8

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-PTK6 (ABIN969373)

Park, Lee, Lee: "Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG." dans: Journal of biochemistry, Vol. 119, Issue 2, pp. 235-9, (1997) (PubMed).

Détails sur PTK6

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Autre désignation: PTK6 (PTK6 Produits)

Synonymes: anticorps BRK, anticorps Sik, anticorps Tksk, anticorps tks, anticorps zgc:153964, anticorps protein tyrosine kinase 6, anticorps PTK6 protein tyrosine kinase 6, anticorps PTK6 protein tyrosine kinase 6b, anticorps PTK6, anticorps Ptk6, anticorps ptk6b

Sujet:

Description: PTK6 (protein tyrosine kinase 6, BRK or FLJ42088), with 451-amino acid protein (about 52 kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

Aliases: BRK, FLJ42088

Poids moléculaire: 52 kDa

ID gène: 5753

HGNC: 5753