PTK6 anticorps

N° du produit ABIN969373

Cet anticorps Souris Monoclonal détecte spécifiquement PTK6 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour PTK6 anticorps (ABIN969373)

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTK6 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2H12B8

Détail du produit anti-PTK6 anticorps

Fonction: PTK6 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human PTK6 expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-PTK6 (ABIN969373)

Park, Lee, Lee: "Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG." dans: Journal of biochemistry, Vol. 119, Issue 2, pp. 235-9, (1997) (PubMed).

Détails sur PTK6

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Autre désignation: PTK6

Sujet: PTK6 (protein tyrosine kinase 6, BRK or FLJ42088), with 451-amino acid protein (about 52 kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

Poids moléculaire: 52 kDa

ID gène: 5753

UniProt: Q13882