PTK6 anticorps (PTK6 Protein tyrosine Kinase 6)

Details for Product anti-PTK6 Antibody No. ABIN966923, Fournisseur: Connectez-vous pour afficher
Antigène
  • BRK
  • Sik
  • Tksk
  • tks
  • zgc:153964
  • protein tyrosine kinase 6
  • PTK6 protein tyrosine kinase 6
  • PTK6 protein tyrosine kinase 6b
  • PTK6
  • Ptk6
  • ptk6b
Reactivité
Humain
159
51
30
2
Hôte
141
20
Clonalité
Monoclonal
Conjugué
Cet anticorp PTK6 est non-conjugé
7
7
7
4
4
4
2
2
2
2
2
2
2
2
2
2
2
Application
ELISA
118
81
46
26
23
13
8
4
3
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Isotype IgG2b
Specificité Ni-NTA purified truncated recombinant PTK6 expressed in E. Coli strain BL21 (DE3).
Purification Antibodies are purified by protein A affinity chromatography
Plasmids, Primers & others Plasmids, Primers & others PTK6 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation PTK6 (PTK6 Antibody Extrait)
Sujet PTK6 (protein tyrosine kinase 6, BRK or FLJ42088),with 451-amino acid protein (about 51kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.
ID gène 5753
Indications d'application ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Stock -20 °C
Produit citée dans: Park, Lee, Lee: "Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG." dans: Journal of biochemistry, Vol. 119, Issue 2, pp. 235-9, 1997 (PubMed).

Background publications Lee, Strunk, Spritz: "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes." dans: Oncogene, Vol. 8, Issue 12, pp. 3403-10, 1993 (PubMed).

Ottilie, Raulf, Barnekow, Hannig, Schartl: "Multiple src-related kinase genes, srk1-4, in the fresh water sponge Spongilla lacustris." dans: Oncogene, Vol. 7, Issue 8, pp. 1625-30, 1992 (PubMed).

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