PTK6 anticorps

N° du produit ABIN966923

Détail du produit anti-PTK6 anticorps

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp PTK6 est non-conjugé

Application: ELISA

Specificité: Ni-NTA purified truncated recombinant PTK6 expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Références pour anticorps anti-PTK6 (ABIN966923)

Park, Lee, Lee: "Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG." dans: Journal of biochemistry, Vol. 119, Issue 2, pp. 235-9, (1997) (PubMed).

Détails sur PTK6

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Autre désignation: PTK6 (PTK6 Produits)

Synonymes: anticorps BRK, anticorps Sik, anticorps Tksk, anticorps tks, anticorps zgc:153964, anticorps protein tyrosine kinase 6, anticorps PTK6 protein tyrosine kinase 6, anticorps PTK6 protein tyrosine kinase 6b, anticorps PTK6, anticorps Ptk6, anticorps ptk6b

Sujet: PTK6 (protein tyrosine kinase 6, BRK or FLJ42088),with 451-amino acid protein (about 51kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

ID gène: 5753