PTK6 anticorps (N-Term)

N° du produit ABIN392105

Il existe 2+ publications pour ce produit. L’anticorps anti-PTK6 Polyclonal Lapin est utilisé pour la détection de PTK6 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour PTK6 anticorps (N-Term) (ABIN392105)

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTK6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB3073-3074

Détail du produit anti-PTK6 anticorps

Épitope: AA 11-41, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BRK (PTK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of human BRK (PTK6).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PTK6 (ABIN392105)

Xu, Ye, Wu, He, Tan, Xiao, Wu, Yu, Mai, Li, Peng, Huang, Li, Zhang, Zhu, Qin: "Overexpression of PTK6 predicts poor prognosis in bladder cancer patients." dans: Journal of Cancer, Vol. 8, Issue 17, pp. 3464-3473, (2018) (PubMed).

Chen, Ma, Cao, Huang, Zeng, Wen: "Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma." dans: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 317, (2014) (PubMed).

Détails sur PTK6

Antigène: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Autre désignation: BRK (PTK6)

Sujet: PTK6 is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation.

Poids moléculaire: 51834

ID gène: 5753

NCBI Accession: NP_001243287, NP_005966

UniProt: Q13882