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Dual Specificity Phosphatase 3 (DUSP3) (AA 157-185), (C-Term) anticorps

DUSP3 Reactivité: Humain WB, IHC (p), FACS Hôte: Lapin Polyclonal RB5730 unconjugated
N° du produit ABIN392859
  • Antigène Voir toutes Dual Specificity Phosphatase 3 (DUSP3) Anticorps
    Dual Specificity Phosphatase 3 (DUSP3)
    Épitope
    • 15
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 157-185, C-Term
    Reactivité
    • 40
    • 21
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 51
    • 7
    Lapin
    Clonalité
    • 51
    • 7
    Polyclonal
    Conjugué
    • 26
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Inconjugué
    Application
    • 40
    • 23
    • 14
    • 13
    • 13
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This DUSP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-185 amino acids from the C-terminal region of human DUSP3.
    Clone
    RB5730
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DUSP3 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    Dual Specificity Phosphatase 3 (DUSP3)
    Autre désignation
    DUSP3 (DUSP3 Produits)
    Synonymes
    anticorps dusp3, anticorps si:bz18k17.3, anticorps si:rp71-18k17.3, anticorps VHR, anticorps RGD1560049, anticorps 2210015O03Rik, anticorps 5031436O03Rik, anticorps T-DSP11, anticorps dual specificity phosphatase 3, anticorps dual specificity phosphatase 3b, anticorps dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related), anticorps DUSP3, anticorps dusp3b, anticorps Dusp3
    Classe de substances
    Viral Protein
    Sujet
    DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. The gene for this protein maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer.
    Poids moléculaire
    20478
    ID gène
    1845
    NCBI Accession
    NP_004081
    UniProt
    P51452
    Pathways
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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