TBK1 anticorps (AA 563-577)

N° du produit ABIN400648

Cet anticorps Souris Monoclonal détecte spécifiquement TBK1 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Chien.

Aperçu rapide pour TBK1 anticorps (AA 563-577) (ABIN400648)

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TBK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 108A429

Détail du produit anti-TBK1 anticorps

Épitope: AA 563-577

Specificité: This antibody recognizes Human TANK-Binding Kinase 1 (TBK1/NAK).

Réactivité croisée (Details): Species reactivity (expected):Bovine, Canine (Dog), Mouse and Rat.
Species reactivity (tested):Human.

Attributs du produit: Synonyms: NAK, TANK-binding kinase 1, T2K, NF-kappa-B-activating kinase

Purification: Protein G Chromatography

Immunogène: A synthetic peptide corresponding to amino acids 563-577 of Human TBK1 - KLHconjugated. AA Sequence: YYQFKKDKAERRLAYCRemarks: This sequence is 100% conserved between Human, Mouse, Rat, Dog and Cow.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, 0.05 % Sodium Azide, 0.2 % Gelatin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur TBK1

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Autre désignation: TBK1

Sujet: NFkappaB-activating kinase (NAK) also known as TANK binding kinase-1 (TBK1) or tumor necrosis factor receptor-associated factor 2-associated kinase (T2K) is a serine/threonine protein that belongs to the IkB kinase (IKK) family. Similar to IKK alpha and beta, NAK induces IkB degradation and NF-kB activity. NAK is activated by phorbol ester tumour promoters and growth factors, whereas catalytically inactive NAK specifically inhibits activation of NF-kB by protein kinase C-epsilon (PKCepsilon). NAK specifically phosphorylates IkB alpha on Serine 36 and NFkB subunit RelA (p65) on Serine 536. NAK is also known to interact with TANK, TRAF-2 and TRIF.Synonyms: NAK, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1

ID gène: 29110

UniProt: Q9UHD2

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome