TDP1 anticorps (N-Term)

N° du produit ABIN400858

Cet anticorps Souris Monoclonal détecte spécifiquement TDP1 dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TDP1 anticorps (N-Term) (ABIN400858)

Antigène: TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TDP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: AT1F2

Détail du produit anti-TDP1 anticorps

Épitope: AA 1-298, N-Term

Specificité: The antibody recognizes human TDP1. Other species not tested.

Attributs du produit: Synonyms: Tyrosyl-DNA phosphodiesterase 1

Purification: Protein-G affinity chromatography

Immunogène: Recombinant human TDP1 (1-298 aa) purified from E. coli

Isotype: IgG2b

Information d'application

Indications d'application: ELISA. Western blot: 1/1,000-1/2,000. Immunohistochemistry on Paraffin Sections: 5 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur TDP1

Antigène: TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

Autre désignation: TDP1

Sujet: Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily and contains two PLD phosphodiesterase domains. Mutations in TDP1 are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1) by interfering with DNA transcription or by inducting apoptosis in postmitotic neurons.Synonyms: Tyrosyl-DNA phosphodiesterase 1

ID gène: 55775

UniProt: Q9NUW8