WRNIP1 anticorps (Internal Region)
Aperçu rapide pour WRNIP1 anticorps (Internal Region) (ABIN401271)
Antigène
Voir toutes WRNIP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- This antibody detects WHIP1. Cross reactivity with WHIP2 protein (isoform2) from human sources is expected based on high homology (BLAST).
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Réactivité croisée (Details)
- Species reactivity (expected):Mouse, Rat, Monkey (100 %)Species reactivity (tested):Human.
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Purification
- Immunoaffinity chromatography
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Immunogène
- Synthetic peptide corresponding to an internal region of the WHIP1 protein
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Isotype
- IgG
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Indications d'application
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ELISA: 1: 10,000 - 1: 40,000. Western blot: 1: 500 - 1: 2,000, detects a band of approximately 96.0 kDa (predictedmolecular weight: 72.2 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.10 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
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Autre désignation
- ATPase WRNIP1
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Sujet
- Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. Werner helicase interacting protein 1 (WHIP) interacts with the N-terminal portion of Werner protein, which contains an exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene product may influence the aging process. A second isoform exists (WHIP2).Synonyms: WHIP, WRNIP1, Werner helicase-interacting protein 1
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ID gène
- 56897
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NCBI Accession
- NP_064520
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UniProt
- Q96S55
Antigène
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