ITGAL anticorps

N° du produit ABIN452277

Cet anticorps anti-ITGAL est un anticorps Monoclonal produit chez le Rat, détectant ITGAL dans FACS, IP, Func et IHC (fro). Convient pour Souris.

Aperçu rapide pour ITGAL anticorps (ABIN452277)

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGAL est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: M17-4

Détail du produit anti-ITGAL anticorps

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Attributs du produit: Synonyms: Integrin alpha-L, LFA1, LFA-1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocytefunction-associated molecule 1 alpha chain, CD11 antigen-like family member A

Purification: Protein-G affinity chromatography

Immunogène: C57BL/6 mouse splenic secondary cytotoxic T lymphocytes

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: 1 μg/mL. Immunoprecipitation. Immunohistochemistry on frozen sections: acetone fixation (Positive tissue: mouse spleenor thymus). Functional application. Blocking.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur ITGAL

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Autre désignation: CD11a / ITGAL

Sujet: CD11a (LFA-1 alpha) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. LFA-1 is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of LFA-1 to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. LFA-1 is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions.Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain

UniProt: P24063

Pathways: Activated T Cell Proliferation, Integrin Complex