ELK1 anticorps (pSer383)

N° du produit ABIN452640

Cet anticorps anti-ELK1 est un anticorps Souris Monoclonal détectant ELK1 dans EIA. Adapté pour Humain.

Aperçu rapide pour ELK1 anticorps (pSer383) (ABIN452640)

Antigène: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ELK1 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Clone: B4A12

Détail du produit anti-ELK1 anticorps

Épitope: pSer383

Specificité: Reactive to Serine383 phosphorylated Human ELK-1 peptide fragment conjugated with KLH or the peptide-BSA conjugate. Not reactive to unconjugated Serine383 phosphorylated Human ELK-1 peptide, KLH or BSA.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: Elk-1, ETS domain-containing protein Elk-1

Purification: Affinity Chromatography on Protein G.

Immunogène: Peptide of a phosphorylated fragment of ELK1 (pSer383) conjugated with KLH.

Isotype: IgG1

Information d'application

Indications d'application: Indirect ELISA: The suggested antigen Coating quantity is 1 μg/mL of peptide/or peptideconjugating in pH 9.5 carbonate buffer, 100 μL/well.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.0 without preservatives

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur ELK1

Antigène: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Autre désignation: ELK1

Sujet: ELK1 belongs to the EST transcription factor family. Proteins in the family have a unique DNA binding domain that binds to conserved DNA sequences. Phosphorylation of ELK1 at Serine 383 and 389 by mitogen-activated protein kinases (MAPKs) activates ELK1. The binding of ELK1 to target sequences is also regulated by its co-factor, serum response factor (SRF), by alternative splicing, and by SUMOylation. ELK1 regulates the transcription of c-fos and genes encoding cytoskeleton proteins, and was found to play a role in longterm memory formation, drug addiction and other neurological disorders.Synonyms: ETS domain-containing protein Elk-1, Elk-1

ID gène: 2002

UniProt: P19419

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling