Caldesmon anticorps (Middle Region)
Aperçu rapide pour Caldesmon anticorps (Middle Region) (ABIN452795)
Antigène
Voir toutes Caldesmon (CALD1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- This antibody detects Caldesmon at Center.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogène
- KLH conjugated synthetic peptide selected from the Center region of human CALD1
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Indications d'application
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Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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Autre désignation
- Caldesmon
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Sujet
- CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction.Synonyms: CAD, CALD1, CDM
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Poids moléculaire
- 93250 Da
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ID gène
- 800
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NCBI Accession
- NP_004333
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UniProt
- Q05682
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Pathways
- Myometrial Relaxation and Contraction
Antigène
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